In the original Louisiana Highway system in use prior to 1955, LA 111 was part of three different routes. The north–south portion was a small part of State Route 143, a designation which encompassed several disconnected roadways running parallel to the Sabine River between Starks and Logansport. The east–west section made up the majority of State Route 138 as far as Anacoco then continued east of town as State Route 414. These routes were designated in two acts of the state legislature in 1926 and 1928, adding to the original 98 routes defined in 1921.
The modern LA 111 was created in 1955 when the Louisiana Department of Highways renumbered the entire state highway system.
Class "B": La 111—From a junction with La-US 190 at or near Junction through or near Evans to a junction with La 8 at or near Burr Ferry.Class "C": La 111—From a junction with La 8 at or near Burr Ferry through or near Haddins Ferry and Anacoco to a junction with La 117 north of Leesville.
— 1955 legislative route description